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10.1111/j.1432-1033.1994.tb18550.x 61 MuecklerM.ThorensB

They also introduced mutations that optimized the enzymes overall kinetics with the goal of driving the gluten peptide levels below the threshold for toxicity, which is estimated at 50 milligrams per day, and doing so within a physiologically relevant timeframe (7)

In contrast, both TLYY-treated groups markedly ameliorated this DSS-induced colon shortening, with the TLYYH group showing a more pronounced effect (Figures 1D, E)